产品货号:
Z11692
中文名称:
ATF3抗体
英文名称:
Anti-ATF3 Antibody
产品规格:
100μg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-ATF3 Antibody |
指标别名 | Cyclic AMP-dependent transcription factor ATF-3;cAMP-dependent transcription factor ATF-3;Activating transcription factor 3;ATF3 |
克隆性 | Polyclonal |
检验物种 | human |
应用范围 | ELISA,WB |
基因名称 | ATF3 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | This antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region of human ATF3. |
计算分子量 | 21kDa |
成分 | 0.02M Potassium Phosphate,0.15M Sodium Chloride,pH7.2,0.01% (w/v) Sodium Azide |
纯化方式 | This affinity-purified antibody is directed against human ATF3 and is useful in determining its presence in various assays including ELISA and western blotting.This polyclonal antibody recognizes over-expressed ATF3 protein found in various expression systems.?Reactivity is observed against human ATF3.Cross-reactivity with ATF3 from other mammalian sources has not been tested. |
浓度 | 1.0mg/mL by UV absorbance at 280nm |
产品形态 | 溶液 |
保存条件 | Store vial at -20℃ prior to opening.Aliquot contents and freeze at -20℃ or below for extended storage.Avoid cycles of freezing and thawing.Centrifuge product if not completely clear after standing at room temperature.This product is stable for several weeks at 4℃ as an undiluted liquid.Dilute only prior to immediate use.Expiration date is one (1) year from date of opening. |
背景资料 | ATF3,or Activating Transcription Factor 3,is a member of mammalian activation TF/CREB protein family of transcription factors.ATF3 binds the cAMP response element (cre) (consensus:5'-gtgacgt[ac][ag]-3'),a sequence present in many viral and cellular promoters.However,ATF3 represses rather than activates transcription from promoters with ATF sites stabilizing inhibitory co-factors at the promoter.Alternate splicing forms of ATF3,called ATF3 delta Zip,lack the leucine zipper domain and do not bind DNA.ATF3 delta Zip stimulates transcription,presumably by sequestering inhibitory co-factors away from the promoter.Human ATF3 (SwissProt 18847) is a 20575 Da protein composed of 181 amino acids. |
Uniprot ID | P18847 |
基因名全称 | Cyclic AMP-dependent transcription factor ATF-3 |
推荐稀释比 | ELISA:1:5,000 - 1:20,000 WB:1:200 - 1:2000 |
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